121 / 150
Results:
The response rate was 20% (N = 148 HCF/731). The overall
influenza vaccination coverage was 19.9% [17.4
–
22.3] (N = 132)
including 35.6% [30.0
–
41.2] (N = 105) for doctors, midwives, and
18.4% [14.9
–
21.8] (N = 111) for nurses, nursing assistants. The overall
coverage was steady for 34% of HCF between 2015 and 2016. Most of
the HCF (87%) organized an information campaign. Main topics were
influenza vaccination strategy (71%), protective measures (54%). 97% of
HCF carried out a vaccination campaign. The organization was shared
between Occupational health team (OHT) (43%), ICT (43%), the
hospital pharmacy (43%). HCW were vaccinated by their colleagues
(53%), OHT (47%), ICT (17%). Posters reminding wearing a mask were
present in 79% of HCF, mainly in the hospital entrance. Masks were
available in the emergency, maternity and pediatric departments.
Discussion and/or Conclusion(s):
Despite broad and well-documen-
ted vaccination campaigns, the coverage remains low for all HCW
categories. Implementing behavioral change in HCW is warranted as
well as providing masks and guidance for appropriate use beside
vaccination.
ID: 4514
Geo-spatial distribution of multi-resistant
Acinetobacter
baumannii
among injured military personnel over the battlefields
in Libya, 2011
–
2015
Mohamed Ali Daw
1
, Aghnyia Dau
2
, Mohamed O Ahmed
3
.
1
Department
of Medical Microbiology &Immunology, Faculty of Medicine, P O BOX
82668, Tripoli-Libya,
2
Department of Surgery, Tripoli Medical centre,
faculty of Medicine, Tripoli Libya,
3
Department of Microbiology and
Parasitology, Faculty of Veterinary medicine, Tripoli Libya
Background:
Libya is a large country in North Africa with the longest
coast in the Mediterranean basin has experienced a major military
fighting since 2011. This was associated with high rate of injury
complicated with emergence of multi-resistant Gram-negative bacilli
particularly
Acinetobacter baumannii.
Aim(s)/Objective(s):
This study aimed to analyse; 1-Molecular charac-
terization of
A
.
baumannii
associated with combat-related injuries.;
2-Geographic and spatial distribution of
A baumannii
in the four
regions (East, West, North & South) of Libya during the conflict period.
Method(s):
A total of 731 different isolates confirmed to A
baumannii
were collected from injured people arriving from the battle-
fields over all the Libya regions within five years-period(2011
–
2015).
Antimicrobial susceptibility and genetic analysis of these isolates were
determined using 12 different antibiotics and pulsed-field gel
electrophoresis (PFGE) to characterize the isolates. spatial-epidemio-
logical analysis was conducted to reflect the changing pattern of
A
baumannii
within the country.
Results:
The genetic analysis showed eight distinct PFGE patterns
varied fromone region to another with a significant increase of Clone 1
in West and East regions. The strains showed a high resistance to all
antibiotics tested with few strains were sensitive to gentamicin and
Carapenems.
Discussion and/or Conclusion(s):
The emergence and spread of
multidrug-resistant
A. baumannii
among Libyan hospitals care settings
suggest an urgent intervention programs to prevent the colonization
and infection by resistant pathogens.
ID: 4534
Point prevalence study of healthcare-associated infections in
primary care hospitals in Helsinki and Uusimaa district, Finland
Marjaana Pitkäpaasi
1
, Jaana-Marija Lehtinen
2
, Mari Kanerva
1
.
1
Inflammation Center, Division of Infectious Diseases, Helsinki University
Hospital and University of Helsinki,
2
Inflammtion Center, Division of
Infectious Diseases, Helsinki University Hospital and University of
Helsinki
Background:
No routine surveillance of healthcare-associated infec-
tions (HAIs) in primary care hospitals in Helsinki and Uusimaa hospital
district (population 1.6 million).
Aim(s)/Objective(s):
To show the burden of HAIs and to introduce a
surveillance method. Data on patient characteristics, prevalence of
catheters and antimicrobials were also collected.
Method(s):
19 municipalities were invited in this voluntary point
prevalence survey (PPS) in September 2015. The infection control
nurses of the hospitals were instructed to collect the data form
the patient charts. The questionnaire (a modification of HALT-2
protocol by ECDC), data analysis and feedback were provided by our
study team.
Results:
Twenty-two hospitals from 16 municipalities participated
and collected data on 2218 inpatients. Of these, 48% were receiving
acute care, 32% rehabilitation, 18% long-term and 2% terminal care. On
the study day, 11% (range by hospital, 4
–
24%) of the patients had
at least one HAI, one-third originating from other hospitals. The most
common HAIs included lower respiratory tract infections (24%),
urinary tract infections (15%) and skin infections (13%). Fourteen
percent had a urine catheter and 18% had a vascular catheter.
Twenty-nine percent were receiving least one antimicrobial. The
most commonly used antimicrobials were cefuroxime, cefalexin and
fluoroquinolones; 41% of the antimicrobials were used for HAI. No
MRSA infections were detected.
Discussion and/or Conclusion(s):
HAI surveillance and prevention in
primary care hospitals require improvement in primary care. PPS is
an appropriate tool. The prevalence of antimicrobial use was high,
especially the fluoroquinolones. Resistant microbes were rare, so far.
ID: 4557
Comparative analysis of adolescent-adult pertussis outbreaks in
schools using mathematical models
Hiroshi Kamano, Sachi Nagao.
Kagawa University, Health Center
Background:
Outbreaks of adolescent-adult pertussis became a public
health problem in various parts of the world. Pertussis outbreaks were
matter of public concern in Japan also.
Aim(s)/Objective(s):
We have studied the epidemiology of pertussis
outbreaks in schools in several countries. In this comparative analysis,
we investigated the epidemic curves of pertussis outbreaks using
regression analysis and an equation relating basic reproduction
number and we developed pertussis simulation models.
Method(s): Outbreak:
Outbreak cases in Europe and Japan were
analyzed. Regression analysis: We analyzed pertussis outbreaks using
a Gompertz function. Simulation model: We used SIR models.
Results:
Regression analysis: We studied the adolescent-adult per-
tussis outbreaks using following equation;
R(t)
=
a
× exp(
−
b
× exp
(
−
c
×
t
)). Simulation model: We investigated the outbreaks using a
SIR model followings,
dS
(
t
)/
d t
=
−
β
×
S
(
t
)
I
(
t
),
dI
(
t
)/
dt
=
β
×
S
(
t
)
I
(
t
)
−
γ
×
I
(
t
),
dR
(
t
)/
d
(
t
) =
γ
×
I
(
t
),
N
=
S
(
t
) +
I
(
t
) +
R
(
t
). The definitions are as
follows:
N
: total population,
S
(
t
): susceptible population,
I
(
t
):
infectious population,
R
(
t
): recovered population,
β
: rate of infection,
α
: rate of attack,
γ
: rate of recovery. We drew simulation curves using
these differential equations.
Discussion and/or Conclusion(s):
We analyzed several cases of
adolescent-adult pertussis outbreaks mathematically. We estimated
basic reproduction numbers of adolescent-adult pertussis in schools.
ID: 4607
A statewide antimicrobial use surveillance: different outcomes for
different health administration systems
Filipe Piastrelli
1
, Ícaro Boszczowski
2
, Denise Brandão
3
,
Maristela Freire
2
, Geraldine Madalosso
4
.
1
Hospital Sapopemba,
2
Hospital das Clínicas, FMUSP,
3
Centro de Vigilância Epidemiologica
Alexandre Vranjac, Sao Paulo,
4
MPH, Sao Paulo State Health Department
Background:
As increasing healthcare acquired infections caused by
multidrug resistant organisms (MDRO), antibiotic use surveillance
systems play a role in improving this practice.
Aim(s)/Objective(s):
This study describes a statewide antibiotic use
surveillance system in São Paulo, Brazil.
Abstracts of FIS/HIS 2016
–
Poster Presentations / Journal of Hospital Infection 94S1 (2016) S24
–
S134
S116