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detailing invasive pulmonary aspergillosis in previously immunocom-

petent patients with influenza A.


We describe two suspected cases of invasive

pulmonary aspergillosis post influenza in previously immunocompe-

tent patients occurring in Glasgow in 2015



We discuss the details of these cases and compare to

previously published case reports of aspergillosis post influenza in the



Invasive pulmonary aspergillosis can occur in previously

immunocompetent influenza A patients.

Discussion and/or Conclusion(s):

Invasive pulmonary aspergillosis

is a rare complication during or following influenza infection and can

occur in previously immunocompetent patients with influenza A.

ID: 5140

A rare case of fungal keratitis

Tara Moshiri


, Craig Wilde


, Susan Elizabeth Snape




Department of

Microbiology, Nottingham University Hospitals,


Department of

Ophthalmology, Nottingham University Hospitals


Scopulariopsis species are common soil saprophytes

widely distributed in nature, previously isolated from plant debris, air

and moist indoor environments. S. brevicaulis appears to be the most

commonly isolated species with S. gracilis being the second most

common. Ocular involvement has only rarely been reported and there

remains a paucity of cases of Scopulariopsis keratitis within the



This is a case of highly unusual Scopulariopsis

gracilis fungal keratitis occurring in the interface between graft and

host following a descemets stripping endothelial keratoplasty in

which a contaminated graft was transplanted. To the best of our

knowledge this is the first time Scopulariopsis gracilis fungal keratitis

is reported and given its incidence following the implantation of a

contaminated endothelial keratoplasty.


The infection likely occurred secondary to contamination

of the dextran transport medium in which the human cornea was

transferred from an eye bank. Scopulariopsis gracilis was subsequently

isolated by the reference laboratory.


The slow growth of fungus was only detected on day 3 of

culture. The sample was however released prior to this and implanted

on day 2. Subconjunctival dexamethasone postoperatively may

have encouraged the rapid growth of the fungus. The occular fungal

infiltrates first enlarged despite therapy but later cleared after

changing anti-fungal regime.

Discussion and/or Conclusion(s):

Patient had good treatment

response with complete resolution of the fungal keratitis. Diagnosis

was made promptly and treatment initiated early (topical G vorico-

nazole & Amphotericin as well as oral Voriconazole & Itraconazole).

The infected graft was removed promptly with repeat intracameral

injections of anti-fungal agents.

ID: 5153

A prospective surveillance study of airborne

Aspergillus fumigatus

in a Tertiary Referral Hospital

Tom Rogers


, Katie Dunne


, Alida Fe Talento


, Niamh Murphy



Lisa Fetherstone


, Catherine O



, Brian O






College & St James

s Hospital,


Trinity College Dublin,


St James


Hospital Dublin


Aspergillus fumigatus

is a major fungal pathogen trans-

mitted by the airborne route. Excavation of soil during construction/

renovation is thought to increase the spore burden and risk of noso-

comial acquisition. Air sampling is performed for hospital surveillance,

particularly during major construction to ensure engineering controls

are effective.


We prospectively collected data over one year on

A. fumigatus

counts in order to obtain baseline levels in advance of a

major build.


Air sampling was performed twice-monthly at 13 hospital

locations. Indoor locations included an intensive care unit (ICU), a

Stemcell transplant unit, a Cardio-thoracic ICU, and a respiratory ward,

each with different air handling arrangements. A dual head SAS air

sampler was used to sample 1000L of air. Sabouraud dextrose agar was

used to select

A. fumigatus

colonies, and Roswell Park Memorial

Institute 1640 agar containing itraconazole/voriconazole screened for

triazole resistant

A. fumigatus



Areas with controlled ventilation, and sealed windows,

generally had satisfactory counts. Two wards without controlled

ventilation repeatedly showed high


counts which was

addressed by installing portable HEPA filters. The Stem cell transplant

unit consistently had satisfactory results.

A. fumigatus

CFU counts

outdoors were generally higher than those indoors. Our findings

confirm that adequate environmental control is dependent on having

units/wards with air handling systems that address patients

risk of

developing nosocomial aspergillosis.

Discussion and/or Conclusion(s):

Our results have provided a

valuable baseline in advance of a major construction project and

have allowed for immediate and effective responses in clinical areas

identified with high

A. fumigatus


Topic: General

ID: 4449

Exploring needle stick injuries among health-workers in

Mansoura University Hospitals and awareness of medical students

for common types of hepatitis (A, B, and C)

Muhammed Alaa Ahmed Moukhtar Hammad, Lena Osama Shoaib,

Nihal Mustafa Saleh, Mohamed Issam Kabsha,

Mahmoud Magdi Mohamed Elsayed Ali Abdou, Sara Elhusseini,

Sherouk Reda Elsheiwi, Hadeel Mohamed Morad,

Nervana Mohamed Ashraf Khalil, Muhammed Galal Abou Elela,

Hussam Abdulsalam Gad, Nebal Nash

at El-Naqeib,

Maram Adel Abdel-Magied, Mohamed Galal Moawad Mansi,

Rawan Nahel Ahmed, Mariam MohyEldin Shehata,

Amal Ayman Khafagy, Mahmoud Mesbah Ahmed Albiomy,

Mahmoud Salah Al-agouz, Mariam Mohammed Hisham Daba,

Sayed Mohammed Heiba.

Mansoura Faculty of Medicine


Hepatitis A, B, and C have been encroaching into Egypt


cities in the recent years.


Clinical level- Knowing all health-workers who

had needle stick injury in the year 2015 in Mansoura University

Hospitals andwhether they receivedproper vaccination forHepatitis B:

140 health-workers involved after which awareness talk is done to

ensure they are updated on management of possible hepatitis B afflic-

tion. Academical level: Awareness has been done to medical students

and healthcare workers on 3 major hepatitis in Egypt A, B, and C: 903



Clinical level: survey on needle stick injuries is given to

health-worker where we ensure confidentiality and then we aware of

hepatitis B. Academic Level: A pre-survey is given to amedical student/

healthworker assessing his/her knowledge of hepatitis A, B, and C.

A general talk targeting certain basic info needed to be known by

students and clinicians is then given. A post survey is then given to

assess the talk.


53% of 140 health-workers got injured by a needle stick in the

past 12 months. 81% didn

t file incident report. 90 were not vaccinated

for Hep B and 96 didn

t receive training in management of needle

stick injury. Out of 903 surveyors for general info on Hep, 40%

answered all questions right in the pre-survey and 90% answered them

right on the post-survey.

Discussion and/or Conclusion(s):

More focus is needed to be put on

informing health-workers and medical students on how to prevent

needle stick injury, and they in general need to be aware of the

common types of hepatitis here.

Abstracts of FIS/HIS 2016

Poster Presentations / Journal of Hospital Infection 94S1 (2016) S24